The stereochemical identity of the alkene or the resulting moieties can be critical to the beneficial properties of such molecules. Olefin metathesis is class of reactions that allows for transformation of easily accessible, inexpensive C–C double bonds to those that are far more difficult to prepare otherwise, and are of exceptionally high value.. XiMo offers catalysts that are not only highly efficient but afford products with high degrees of stereoselectivity. Our catalysts have already been used in asymmetric Ring Closing Metathesis (ARCM).
link to publication (XiMo unpublished results, based on Hoveyda et al., Nature, 2008, 456, 933-939)
Mo-catalyst are suitable for kinetic resolution of acyclic dienes that contain a heteroatom within the cyclizing chain.
Similarly, catalytic enantioselective desymmetrization (Asymmetric RCM) could also be done with the same catalyst.
link to publication: Hoveyda and Schrock et al J. Am. Chem. Soc. 1998, 9720.; Hoveyda et al. Angew. Chem. Int. Ed. 2010, 49, 34-44.
